Monoclonal Antibody Therapy at OhioHealth

Monoclonal Antibody Therapy at OhioHealth

Monoclonal Antibody Therapy at OhioHealth

Gain a deeper understanding of these therapies for COVID-19 and review the symptoms and high-risk factors necessary to be a candidate for treatment, and the process for receiving the medication.

In published studies, monoclonal antibodies decrease a patient’s viral load, which may reduce the possibility of disease progression and hospitalization. Monoclonal antibody treatment is approved under emergency use authorization from the U.S. Food and Drug Administration (FDA) and has proven to be effective against the COVID-19 variants.


Talk to your doctor

If you have tested positive for COVID-19, have been experiencing symptoms for less than seven days, and have a high-risk factor (as listed below), you may be eligible to receive this treatment. Monoclonal antibodies can also be administered as a preventive measure to high-risk individuals after a known high risk COVID exposure. First, talk with your primary care provider — monoclonal antibody treatment requires a physician referral.


Fast facts about monoclonal antibodies

Joe Gastaldo, MD, OhioHealth’s system medical director of infectious disease, explains how monoclonal antibodies work, which patients the therapy is a good fit for, and the potential side effects and complications.


How the monoclonal antibody treatment process works at OhioHealth

  • All patients must have a physician referral. Talk to your primary care provider.
  • Patients will be contacted to schedule an appointment at one of our dedicated treatment locations. Patients will be called to schedule within 48 hours, but it may take longer over the weekend.
  • Monoclonal antibody treatment is delivered intravenously in one dose. The overall process takes about two hours, which includes setup, getting the treatment, and a one hour observation afterwards.
  • Visitors are not permitted. Patients are welcome to bring a book or reading material.

Cost for the treatment

OhioHealth is providing COVID-19 monoclonal antibody treatments for no cost to our community. We will not bill you for any balance, deductible, copay or coinsurance. However, be aware that if you have insurance, OhioHealth will bill your insurance provider for the cost to administer the treatment. If you do not have insurance, the government will cover the cost to administer the treatment via the CARES Act. Call the OhioHealth Price Line with questions at (614) 566-8707 or (toll free) (844) 393-1035.

COVID-19 symptoms, high-risk factors and exclusion criteria

Qualifying COVID-19 symptoms
  • Chills
  • Cough
  • Diarrhea
  • Documented temperature above 100 F (37.8 C)
  • Fatigue
  • Headache
  • Loss of taste or smell
  • Nasal discharge
  • Nasal obstruction or congestion
  • Nausea or vomiting
  • Shortness of breath
  • Sore throat
  • Subjective fever or feverish feeling
High-risk factors
  • Age 65 or older
  • Cancer
  • Chronic Kidney Disease
  • Chronic liver disease
  • Chronic lung diseases
  • Cystic Fibrosis
  • Dementia or other neurological conditions
  • Diabetes (type 1 or type 2)
  • Disabilities
  • Heart conditions
  • HIV infection
  • Immunocompromised state (weakened immune system)
  • Mental health conditions
  • Overweight and obesity
    • BMI of 35 or higher for adults; above 85th percentile of pediatrics
  • Physical inactivity
  • Pregnancy
  • Sickle cell disease or thalassemia
  • Smoking, current or former
  • Solid organ or blood stem cell transplant
  • Stroke or cerebrovascular disease
  • Substance use disorders
  • Tuberculosis

For more details about these conditions, go to the CDC web site.

Exclusion criteria

Monoclonal antibody treatment is not authorized for use in patients who are:

  • Hospitalized due to COVID-19
  • Receiving oxygen therapy due to COVID-19
  • Receiving chronic oxygen therapy due to an underlying non-COVID-19 related comorbidity, and require an increase in baseline oxygen flow rate due to COVID-19.

Monoclonal antibody infusion locations